FALLS CHURCH, Va. — Great strides have been made with RNAi therapeutics in the short time since the gene-silencing phenomenon was first observed. Still, a number of key issues involving efficacy, safety, and delivery — the “number one problem” — must be addressed before the field can succeed, according to a senior Merck official.
 

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The US Food and Drug Administration has approved Kite Pharmaceuticals' CAR T-cell therapy for large B-cell lymphomas, the New York Times reports.

Kaiser Health News reports that gene therapies could cost more than a million dollars.

Worcester Polytechnic Institute researchers have received a grant to combine biology and computer science for high school students.

In Nature this week: variants associated with obsessive-compulsive disorder, review of key CRISPR enzymes, and more.