FALLS CHURCH, Va. — Great strides have been made with RNAi therapeutics in the short time since the gene-silencing phenomenon was first observed. Still, a number of key issues involving efficacy, safety, and delivery — the “number one problem” — must be addressed before the field can succeed, according to a senior Merck official.
 

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A fire at a Manchester hospital may have destroyed lab equipment and data, the Guardian reports.

Researchers generate a genetic database from skeletal remains from the 1845 Franklin Expedition to the Arctic, Live Science reports.

Researchers in China have begun another trial using CRISPR/Cas9 approaches in cancer patients, according to the Wall Street Journal.

In Science this week: human DNA found in sediments from archeological sites lacking bones, and more.