By Doug Macron

Although one of its inflammatory bowel disease targets has already garnered the attention of a big pharma, Cequent Pharmaceuticals expects its IBD program will advance into the clinic first with an RNAi molecule against a proprietary target, a company official told RNAi News this week.

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In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.