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Cell Signaling Techology s Signal Silence PAK1 and Signal Silence PAK2, Resource Center for Genome Research, Max Planck Institute for Molecular Cell Biology and Genetics, and RNA-Tec s RNA peptide conjugates

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Cell Signaling Technology recently introduced a number of RNAi products, including the SignalSilence PAK1 siRNAs and siRNA kit and the SignalSilence PAK2 siRNAs and siRNA kit. The comp- any also recently launched SignalSilence siRNAs and siRNA kits for Bax, Stat1, and cMyc.


Germany’s Resource Center for Genome Research (RZPD) said this week that its scientists have developed an efficient and economic method to synthesize siRNAs.

According to RZPD, the process involves degrading specific long double-stranded DNA molecules into siRNAs. The siRNAs are now being tested in model experiments in cooperation with the Max Planck Institute for Molecular Cell Biology and Genetics, said RZPD.


RNA-Tec recently began offering custom synthesized RNA peptide conjugates. According to the company, a variety of peptides enhance cellular uptake of oligonucleotides, such as siRNAs, when conjugated to them. RNA-Tec added that with its RNA-peptide conjugates, the linkage between the oligo and peptide is stable or biodegradable.

The Scan

Billions for Antivirals

The US is putting $3.2 billion toward a program to develop antivirals to treat COVID-19 in its early stages, the Wall Street Journal reports.

NFT of the Web

Tim Berners-Lee, who developed the World Wide Web, is auctioning its original source code as a non-fungible token, Reuters reports.

23andMe on the Nasdaq

23andMe's shares rose more than 20 percent following its merger with a special purpose acquisition company, as GenomeWeb has reported.

Science Papers Present GWAS of Brain Structure, System for Controlled Gene Transfer

In Science this week: genome-wide association study ties variants to white matter stricture in the brain, and more.