Skip to main content
Premium Trial:

Request an Annual Quote

Benitec Says USPTO Poised to Finalize Validity Ruling for Key Patent


Benitec said this week that the US Patent and Trademark Office has indicated that it is issuing a re-examination certificate for the company's core US patent, marking the final step in the agency's confirmation of the patentability of the claims within the intellectual property.

The patent, No. 6,573,099, essentially claims the knockdown of gene expression using DNA that transcribes double-stranded RNA. Although it was one of the earliest patents in the RNAi field, it was deemed invalid by the USPTO after re-examination proceedings were initiated by now-defunct expressed RNAi firm Nucleonics.

Nucleonics had been sued by Benitec for infringing the IP, but asked the patent office to review the patent as part of its efforts to fend off the patent-infringement suit. The case was ultimately dismissed, and late last year the USPTO reversed its invalidity ruling (GSN 11/11/2010).

The Scan

Study Reveals Details of SARS-CoV-2 Spread Across Brazil

A genomic analysis in Nature Microbiology explores how SARS-CoV-2 spread into, across, and from Brazil.

New Study Highlights Utility of Mutation Testing in Anaplastic Thyroid Cancer

Genetic mutations in BRAF and RAS are associated with patient outcomes in anaplastic thyroid carcinoma, a new JCO Precision Oncology study reports.

Study Points to Increased Risk of Dangerous Blood Clots in COVID-19 Patients

An analysis in JAMA Internal Medicine finds that even mild COVID-19 increases risk of venous thromboembolism.

Y Chromosome Study Reveals Details on Timing of Human Settlement in Americas

A Y chromosome-based analysis suggests South America may have first been settled more than 18,000 years ago, according to a new PLOS One study.