Arrowhead Research this week published preclinical data demonstrating that its lead hepatitis B drug candidate, dubbed ARC-520, could silence the hepatitis B virus in rodents for up to one month after a single dose.

The data, which were published in Molecular Therapy, also showed that the delivery technology used in ARC-520 could safely and effectively deliver siRNAs targeting coagulation factor VII in non-human primates.

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In PNAS this week: genomic study of group B Streptococcus evolution, selection on the X chromosome in great apes, and more.

Changing the fat and fiber content of people's diets affects their gut microbiome, metabolome, and colon cancer risk, researchers say.

Broken links are found throughout academic publications, and some services are trying to combat such link decay.

Nick Stockton at Wired says that a pause in studying genome-editing tools should be used to find a path forward.