Arrowhead Presents Preclinical Data on HBV Candidate, Subcutaneous Delivery Tech | GenomeWeb

Arrowhead Research last week released new preclinical data on its lead drug candidate, the hepatitis B virus treatment ARC-520, reporting that the agent could trigger up to multi-log reductions in the levels of circulating viral antigens, while lowering levels of the virus' replicative intermediates, in mouse models.

The company also provided new non-human primate data on its recently acquired dynamic polyconjugate siRNA-delivery system, showing that tweaks to the technology have enabled subcutaneous delivery with near complete target knockdown.

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