Arrowhead HBV Drug Shows Efficacy in Chimp Model | GenomeWeb

Arrowhead Research said this week that its preclinical hepatitis B treatment ARC-520 was found to trigger a greater than 90 percent reduction in circulating HBV DNA in a chimpanzee chronically infected with the virus.

The chimpanzee has been infected for more than 30 years and has high viral-titer and antigenemia and nearly 100 percent of hepatocytes stain positive for HBV, the company said.

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