Skip to main content
Premium Trial:

Request an Annual Quote

Arrowhead Gets OK for Delivery Technology Patent


Arrowhead Research this week announced that it has received notice from the US Patent and Trademark Office that it will be issued a patent on its dynamic polyconjugate siRNA delivery technology.

Dynamic polyconjugates, or DPCs, are nanoparticles composed of an amphipathic polymer to which shielding agents such as polyethylene glycol, as well as targeting ligands, are reversibly attached, according to Arrowhead. The company acquired the technology when it bought Roche's RNA drug assets last year (GSN 10/27/2011).

According to Arrowhead, the USPTO said it will grant a patent on an application entitled “Compositions for Targeted Delivery of siRNA,” which covers compositions, methods, and uses for a new formulation of the DPCs.

The Scan

Alzheimer's Risk Gene Among Women

CNN reports that researchers have found that variants in MGMT contribute to Alzheimer's disease risk among women but not men.

Still Hanging Around

The Guardian writes that persistent pockets of SARS-CoV-2 in the body could contribute to long COVID.

Through a Little Spit

Enteric viruses like norovirus may also be transmitted through saliva, not just the fecal-oral route, according to New Scientist.

Nature Papers Present Method to Detect Full Transcriptome, Viruses Infecting Asgard Archaea, More

In Nature this week: VASA-seq approach to detect full transcriptome, analysis of viruses infecting Asgard archaea, and more.