Arrowhead Research announced this week that it has established a new majority-owned subsidiary, Calando Pharmaceuticals, that will take over and expand upon the RNAi therapeutics activities of another Arrowhead company, Insert Therapeutics.

According to California Institute of Technology researcher Mark Davis, who is a co-founder of both Insert and Calando, the new company is designed to merge the delivery technology of Insert — which will no longer work in the RNAi field — with additional RNAi technology just licensed from CalTech.

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While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.