NEW YORK (GenomeWeb) – As it presses ahead with Phase II development of its flagship hepatitis B therapy ARC-520, Arrowhead Research is banking on the drug's ability to cut levels of the virus's surface antigen (s-antigen), a key indicator of active infection, the company's top executive said this week.

According to Arrowhead President and CEO Chris Anzalone, treating HBV has proven especially challenging because blocking viral replication alone is not enough to clear the virus, unlike with hepatitis C.

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In Nature this week: association between genome-wide homozygosity and traits like height and cognitive ability, improved CRISPR-Cas9 editing, and more.

A survey examines how age, political leanings, and more influence how Americans view certain scientific topics, the Associated Press reports.

A researcher who pleaded guilty to making false statements in research reports has been sentenced to four and a half years in prison and must pay $7.2 million back to the NIH.

The BabySeq project to study the risks and benefits of sequencing newborns is underway.