Arrowhead Aims for HBV IND in Early 2013, Releases Preclinical Data from Program | GenomeWeb

Just months after adding a hepatitis B treatment to its pipeline, Arrowhead Research's top official this week said that the company expects the program to yield an investigational new drug application in the first half of next year.

Arrowhead, which just released its fiscal second-quarter financial results, also announced preclinical data showing that siRNAs formulated in the company's proprietary dynamic polyconjugate, or DPC, technology could significantly reduce levels of the viral RNA and DNA in animal models of the disease.

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In Nucleic Acids Research this week: personal genome approach to RNA-seq read alignment, hematopoietic Systems Biology Repository, and more.

A man is using DNA evidence to argue that he is the rightful heir to the baronetcy of Stichill, the Guardian reports.

As part of an effort to get a diverse group of people to donate their DNA for research, some blood donors in the San Diego area will get their genomes sequenced, according to KPBS.

The comment period on the Department of Health and Human Services' proposal to alter the Common Rule has been extended.

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