Skip to main content

Amid Delivery Tech Dispute, Alnylam Forges Collaboration with Precision NanoSystems

Premium

Alnylam Pharmaceuticals announced this week that it has forged an exclusive collaboration with Vancouver, Canada-based Precision Nanosystems to discover and develop novel small lipid nanoparticles using microfluidics, marking the latest in a series of delivery-focused collaborations inked over the past year.

According to the companies, Precision NanoSystems' LNPs are roughly 20 nanometers in size, opening the door to effective siRNA delivery to organs and tissues beyond the liver. Additional terms of the arrangement were undisclosed.

Notably, the deal comes at a time when Alnylam is embroiled in a lawsuit with partner Tekmira Pharmaceuticals over rights to LNP technologies that Tekmira has been developing and Alnylam has been using in certain of its drug candidates including the phase I cancer treatment ALN-VSP (GSN 3/17/2011 & 4/7/2011).

It also comes shortly after two other RNAi delivery collaborations were unveiled, one between Japan's Takeda Pharmaceutical and Korea-based Samyang, and another between Access Pharmaceuticals and an undisclosed international pharmaceutical firm (GSN 4/14/2011).

A number of agreements within the RNAi therapeutics space around delivery technologies, in fact, have been struck recently, involving both big pharmas and companies with a narrower focus. Below is a breakdown of key deals since the beginning of 2010.

deal1.jpg
deal2.jpg

The Scan

UK Funds to Stay Ahead of Variants

The UK has announced a further £29.3 million to stay on top of SARS-CoV-2 variants, the Guardian reports.

Push for Access

In a letter, researchers in India seek easier access to COVID-19 data, Science reports.

Not as Cold

Late-stage trial results are expected soon for an RNA-based vaccine that could help meet global demand as it does not require very cold storage, the New York Times writes.

Genome Research Papers on Microbes' Effects on Host Transfer RNA, Honeybee Evolution, Single-Cell Histones

In Genome Research this week: influence of microbes on transfer RNA patterns, evolutionary relationships of honeybees, and more.