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Ambion: Mar 22, 2007

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Ambion has recently introduced the Pre-miR miRNA starter kit, which is designed for “controlling and optimizing miRNA gain-of-function experiments in human cells mediated by synthetic miRNA mimics.”
 
According to the company, the kit includes positive and negative control Pre-miR miRNA precursors, which are chemically modified double-stranded RNA molecules designed to mimic endogenous mature miRNA molecules, as well as a transfection agent.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.