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Alnylam Says Key Tuschl-II Claims Upheld by Japanese Patent Office


Alnylam Pharmaceuticals this week announced that the Japanese Patent Office has upheld certain key claims within the company's Tuschl-II patent during invalidation proceedings initiated at the request of Bio Think-Tank, a Japanese company.

Tuschl-II is a family of patents and patent applications broadly related to siRNAs, between 21 to 23 nucleotides long, and with 2- to 3-nucleotide-long 3' overhangs, that can target specific mRNA degradation in mammals. It is named for Rockefeller University researcher and Alnylam co-founder Thomas Tuschl, and is exclusively licensed to Alnylam.

The Scan

More Boosters for US

Following US Food and Drug Administration authorization, the Centers for Disease Control and Prevention has endorsed booster doses of the Moderna and Johnson & Johnson SARS-CoV-2 vaccines, the Washington Post writes.

From a Pig

A genetically modified pig kidney was transplanted into a human without triggering an immune response, Reuters reports.

For Privacy's Sake

Wired reports that more US states are passing genetic privacy laws.

Science Paper on How Poaching Drove Evolution in African Elephants

In Science this week: poaching has led to the rapid evolution of tuskless African elephants.