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Alnylam Says Chinese Patent Office to Grant Patent on RNAi Molecules


Alnylam Pharmaceuticals this week announced that it has been notified that the Chinese patent office intends to grant a patent, assigned to the Max Plank Society and exclusively licensed to Alnylam, covering siRNAs.

According to the company, the patent application — No. 01820900.9 — is part of the so-called Tuschl II family of intellectual property and covers the compositions, methods, uses, and systems of double-stranded RNAs having key structural elements including a length of between 19 and 25 nucleotides; one or more 3' overhangs at the ends of the molecule; and chemical modifications on the 3' end.

The application also claims the use of such molecules to modulate gene function in mammals or pathogen-derived genes in vitro and in vivo, Alnylam said.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.