Alnylam Reports Positive Phase II Data on TTR Drug, Aims for Phase III by Year End | GenomeWeb

Alnylam Pharmaceuticals this week announced positive clinical results from an ongoing phase II trial of ALN-TTR02, an investigational treatment for TTR-mediated amyloidosis, reporting that the drug was able to knock down levels of the protein that causes the disease by as much as 93 percent.

The gene inhibition was rapid, dose-dependent, and durable, Alnylam said. Additionally, ALN-TTR02 was generally safe and well tolerated in the trial — all of which puts the company on track to move into phase III before the end of the year.

Get the full story with
GenomeWeb Premium

Only $95 for the
first 90 days*

A trial upgrade to GenomeWeb Premium gives you full site access, interest-based email alerts, access to archives, and more. Never miss another important industry story.

Try GenomeWeb Premium now.

Already a GenomeWeb Premium member? Login Now.
Or, See if your institution qualifies for premium access.

*Before your trial expires, we’ll put together a custom quote with your long-term premium options.

Not ready for premium?

Browse our free articles
You can still register for access to our free content.

In Nucleic Acids Research this week: personal genome approach to RNA-seq read alignment, hematopoietic Systems Biology Repository, and more.

A man is using DNA evidence to argue that he is the rightful heir to the baronetcy of Stichill, the Guardian reports.

As part of an effort to get a diverse group of people to donate their DNA for research, some blood donors in the San Diego area will get their genomes sequenced, according to KPBS.

The comment period on the Department of Health and Human Services' proposal to alter the Common Rule has been extended.

Sponsored by
HTG Molecular

This webinar will discuss potential clinical applications for miRNA signatures and a novel, extraction-free miRNA profiling technology for advancing biomarker discovery.