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Alnylam, Qiagen, Galapagos, BioFocus, PerkinElmer, Invitrogen, Kreatech


Alnylam Licenses RNAi Patents to Qiagen

Alnylam Pharmaceuticals said this week that it has granted Qiagen non-exclusive access to use technology covered under the Kreutzer-Limmer patent family to provide RNAi research products and services.

The intellectual property covers small interfering RNAs and their use to mediate RNAi in mammalian cells.

Qiagen already offers siRNA libraries and high-throughput siRNA synthesis technology.

Galapagos to Acquire BioFocus for $36.5 Million in Stock

Dutch biotech firm Galapagos said this week that it has reached an agreement to acquire UK-based BioFocus for £20.2 million ($36.5 million).

According to the terms of the offer, Galapagos will buy the entire issued share capital of BioFocus by Oct. 12. BioFocus will then become part of the Galapagos group with a 30 percent stake in the firm.

Galapagos CEO Onno van de Stolpe said that the acquisition is expected to enhance the company's position in the drug discovery market.

"We are truly impressed by their drug discovery capabilities [and] we believe that these will greatly accelerate our programs in bone and joint diseases," van de Stolpe said.

PerkinElmer, Invitrogen to Co-Market Cellular Screening Technologies

PerkinElmer and Invitrogen this week said they have inked a co-marketing agreement that will integrate PerkinElmer's CellLux Fluorescence Cellular Screening Platform for cellular screening and Invitrogen's Voltage Sensor Probes ratiometric ion channel reagents.

Peter Coggins, president of PerkinElmer life and analytical sciences, said that the agreement will help both firms' customers "in transitioning to cellular screening, to drive fundamental productivity improvements into the drug discovery and development process."

Nick Ecos, vice president and general manager of Invitrogen's drug discovery solutions business, said the company would seek similar co-marketing agreements in the future. "We will continue to pair our technologies with those from industry-leading companies like PerkinElmer in order to capitalize on our integrated strength," Ecos said.

Financial details were not discussed.

Kreatech Says ISB Collaboration Will Result in New Labeling Kits

Kreatech Biotechnology said this week that its ongoing collaboration with the Institute of Systems Biology will result in two new nucleic acid labeling kits.

ISB has optimized Kreatech's kits, which are based on its Universal Linkage System technology, for bacterial expression profiling and chromatin immunoprecipitation microarray (ChIP-on-chip) assays.

Brent Keller, Kreatech's vice president of commercial applications, told GenomeWeb News today that the company "will be coming out with ULS kits for these applications" based on the ISB collaboration. Keller did not provide a timeline for the commercial release of the new kits, however.

The company previously released kits for array comparative genome hybridization applications and gene-expression analysis.

The Scan

Two J&J Doses

Johnson & Johnson says two doses of its SARS-CoV-2 vaccine provides increased protection against symptomatic COVID-19, CNN reports.

Pfizer-BioNTech Vaccine Response in Kids

The Pfizer-BioNTech SARS-CoV-2 vaccine in a lower-dose format appears to generate an immune response among children, according to the Washington Post.

Chicken Changes to Prevent Disease

The Guardian writes that researchers are looking at gene editing chickens to help prevent future pandemics.

PNAS Papers on Siberian Dog Ancestry, Insect Reproduction, Hippocampal Neurogenesis

In PNAS this week: ancestry and admixture among Siberian dogs, hormone role in fruit fly reproduction, and more.