Alnylam Pharmaceuticals this week released an update for its key financial and clinical goals for 2010. However, the guidance was primarily a confirmation of previous estimates.

"We are … excited about the next 12 to 18 months as we … fulfill the RNAi 2010 goals that we described two years ago," Alnylam President and COO Barry Greene said in a statement. "Over this period, we expect to have four RNAi therapeutic programs in clinical development … providing us with the opportunity to demonstrate human proof of concept for multiple programs."

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In Science this week: factors influencing retrotransposon integration sites, and more.

A bioethicist argues for the responsible use of germline gene editing.

Some breweries are using DNA-based testing to determine whether unwanted bacteria are affecting their beers, The Verge reports.

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