Alnylam Pharmaceuticals this week released new preclinical data from programs in beta-thalassemia and erythropoiesis — indications from which the company could select its newest pipeline candidate.

Alnylam, which presented the data at the American Society of Hematology annual meeting, said that it and collaborators showed that the systemic administration of a lipid nanoparticle-formulated siRNA targeting the gene transmembrane protease, serine 6, triggered an increase in hepcidin mRNA levels in mouse models of iron overload in beta-thalassemia.

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Two researchers have found that behavioral genetic defenses in criminal cases don't tend to affect outcomes, according to Popular Science.

Researchers report that while host genetics influence the oral microbiome, they don't appear to affect cavity-causing microbes, the Economist says.

Pandas' gut microbiomes change as what they eat changes with the seasons, writes Discover's Inkfish blog.

In PLOS this week: comparative genomic study of malaria-linked macaque parasite, search for apple root reference genes, and more.