Alnylam Presents Positive Phase II Data on ATTR Drug, Starts Enrollment in Phase III | GenomeWeb

Alnylam Pharmaceuticals this week announced positive data from a phase II trial of its TTR-mediated amyloidosis drug patisiran, formerly ALN-TTR02, showing that the drug triggered "robust and statistically significant" inhibition of its target protein.

The company also announced that it has begun a phase III trial of the drug in patients with a manifestation of the disease called familial amyloidotic polyneuropathy, or FAP.

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