Alnylam Pharmaceuticals last week released preclinical data on ALN-CC5, an RNAi-based drug targeting complement component 5 and the newest addition to its product-development pipeline.

The complement system is involved in immunity as a protective mechanism for host defense, according to the company. Dysregulation of the system can create serious complications in a variety of diseases including paroxysmal nocturnal hemoglobinuria, atypical hemolytic-uremic syndrome, myasthenia gravis, and neuromyelitis optica.

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In Science this week: the Human Silencing Hub protein complex, and more.

Heads of various research funding agencies discuss how to encourage scientific breakthroughs, ScienceInsider reports.

The Kansas City Star examines issues surrounding newborn genome sequencing.

Researchers say their Research Resource Identifier citation format is catching on, Nature News reports.