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Alnylam Patent Upheld by EPO


Alnylam Pharmaceuticals last week announced that the European Patent Office's board of appeals ruled that claims within one of the company's core patents meet the mandatory requirements under European patent law.

The patent, EP 1214945, claims methods, medicaments, and uses of siRNAs with a double-stranded structure consisting of 15 to 49 nucleotides, according to Alnylam. It is part of the so-called Kreutzer-Limmer patent family.

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.