Alnylam Pharmaceuticals racked up another partnership this week, announcing that it has inked a global development and commercialization deal for its hypercholesterolemia program with The Medicines Company.

For Alnylam, the arrangement represents an important milestone in moving ahead with the program, which includes the phase I intravenous drug ALN-PCS02 and the preclinical subcutaneous agent ALN-PCSsc, as the company had previously disclosed that it would only advance the drug candidates in collaboration with a partner.

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In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.