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Alnylam Pharmaceuticals announced this week that it has filed with UK regulators to begin phase I testing of a subcutaneous version of its TTR-mediated amyloidosis treatment called ALN-TTRsc.

Currently, Alnylam is testing an intravenously delivered form of the drug called ALN-TTR02, which it anticipates entering phase III testing by the end of this year. However, the firm has long been planning to incorporate its GalNAc conjugate delivery technology into its TTR amyloidosis program.

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Wired reports on how genetic genealogy's use in forensics has exploded in the year since an arrest in the Golden State Killer case was made.

Retraction Watch reports that the increase in retracted papers at a journal is due to more resources there to tackle publication ethics.

New York City has settled with a forensic scientist who was fired after questioning a DNA testing approach used by the medical examiner's office, the New York Times reports.

In Nature this week: technique for measuring replication fork movement, WINTHER trial results, and more.

Apr
30
Sponsored by
Lexogen

This webinar will discuss novel long-read transcript sequencing (LRTseq) methods for transcriptome annotation that could increase the efficiency and accuracy of future sequencing projects.

May
21
Sponsored by
Qiagen

This webinar will provide a first-hand look at how a hematology/oncology lab in the UK set up and validated three molecular assays for routine in-house use.