Alnylam Pharmaceuticals last week published preclinical data describing the development of a dendritic cell cancer vaccine enhanced with RNAi.

According to the company, its researchers and collaborators from Radboud University Nijmegen Medical Centre designed siRNAs toward PD-L1 and PD-L2, which are “key co-inhibitory proteins expressed on antigen-presenting cells that strongly limit activation of T-cells needed for a potent immune response to the tumor.”

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A research duo estimates in PLOS One the number of papers that have used misidentified cell lines.

UK's National Institute for Health and Care Excellence approves GlaxoSmithKline's SCID gene therapy despite cost.

Science reports that Brazilian researchers are petitioning for the reversal of budget cuts.

In PLOS this week: gene flow patterns in common ash, guidelines for using morpholinos in zebrafish, and more.