Allergan has halted development of its siRNA-based wet age-related macular degeneration treatment AGN-745 after the drug failed to meet a key efficacy endpoint in a phase II study, a company spokeswoman confirmed this week.

The trial was comparing the effect of three different monthly doses of AGN-745 with Genentech's antibody drug Lucentis, the standard of care for AMD, in treating the subfoveal choroidal neovascularization associated with the disease. Both drugs are administered via intravitreal injection.

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Researchers describe a way to share data while keeping it secure, Agence France Presse reports.

In Science this week: genetic mutations typically associated with esophageal cancer are common in older, healthy individuals, and more.

India's Council of Scientific and Industrial Research has a new director-general, according to ScienceInsider.

A new study links more than a hundred genes to autism spectrum disorder, Discover's D-brief blog reports.

Nov
05
Sponsored by
Sophia Genetics

With the Next Generation Sequencing (NGS), genomes sequencing has been democratized over the last decades with the detection of genomic alterations, thus replacing Sanger sequencing.

Nov
15
Sponsored by
Twist Bioscience

This webinar will discuss how Amyris, a biotechnology company that develops renewable products for a broad range of applications and industries, uses large-scale microbial engineering to support its manufacturing processes.