ADRI Begins Phase I Trial of microRNA Mimic for Mesothelioma | GenomeWeb

NEW YORK (GenomeWeb) – Australia's Asbestos Diseases Research Institute (ADRI) has recently begun enrolling patients in a Phase I trial of a microRNA-based treatment for malignant pleural mesothelioma (MPM), marking the second time a drug based on the small, non-coding RNAs has moved into human testing.

Meanwhile, ADRI continues to plan for a Phase 0 study of the therapy that was supposed to run prior to the Phase I trial, but was put on hold as the institute addressed concerns about how the drug's pharmacokinetics would be evaluated.

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