By Doug Macron

Access Pharmaceuticals last week announced that it has begun an in-house effort to adapt its proprietary vitamin B12-based technology for therapeutic RNAi applications and potentially develop orally delivered drugs.

The technology, dubbed Cobalamin, is based on the body's natural vitamin B12 uptake mechanism, Access CEO Jeff Davis told RNAi News this week. It involves merging a polymer and active pharmaceutical ingredient to make a nanoparticle, which is then coated with the vitamin.

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The US Food and Drug Administration has approved Kite Pharmaceuticals' CAR T-cell therapy for large B-cell lymphomas, the New York Times reports.

Kaiser Health News reports that gene therapies could cost more than a million dollars.

Worcester Polytechnic Institute researchers have received a grant to combine biology and computer science for high school students.

In Nature this week: variants associated with obsessive-compulsive disorder, review of key CRISPR enzymes, and more.