November 07, 2018
Sponsored by
Qiagen

Implementation of a Comprehensive NGS Oncology Panel including MSI and TMB Signatures

GenomeWebinar

Associate Professor, Department of Pathology; Augusta University

This webinar will provide a first-hand look at how a leading pathology lab implemented a next-generation sequencing panel to capture comprehensive molecular tumor profiles.

As cancer genetics evolves and new clinical trials and data emerge, it has become increasingly critical to detect single nucleotide variants, insertions and deletions, as well as measuring copy number variations, microsatellite instability, and tumor mutational burden.

NGS serves as an important tool for such interrogations, but major gaps remain in performance robustness and interpretation algorithms. The implementation of a single assay, combined with an integrated bioinformatics pipeline, that assesses SNVs, indels, CNVs, MSI, and TMB enables efficiencies in sample usage, time, and cost.

Our speaker, Dr. Ravindra Kolhe of Augusta University, will discuss his experience using the new QIAseq Tumor Mutational Burden panel coupled with QIAGEN’s bioinformatic solutions in comparison with a centralized testing model, focusing on:

  • QIAseq TMB panel content
  • Bioinformatics pipeline
  • Ease of adoption/integration
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