Close Menu
October 01, 2020
Sponsored by
Adaptive Biotechnologies

Immune Repertoire Sequencing to Uncover SARS-CoV-2-Specific T Cell Responses and Dynamics

GenomeWebinar

Chief of the Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases at the National Institutes of Health

Bioinformatician, NIAID Collaborative Bioinformatics Resource (NCBR)/Leidos

VP Research for immunoSEQ Dx, Adaptive Biotechnologies

T cells are the adaptive immune system’s first responders to any virus, circulating in the blood to detect and quickly multiply to attack the virus, and also support the development of antibodies by B cells. This central role for T cells makes them a desirable target for assessing the immune response to SARS-CoV-2 infection. 

In this webinar we’ll discuss:

  • Information and early insights from Adaptive Biotechnologies’ open-access ImmuneCODE COVID-19 database
  • Demonstrate how high-throughput sequencing of the T-cell receptor beta repertoire may reveal SARS-CoV-2-specific clonotypes
  • Describe the epidemiology of COVID-19 in a cohort of patient samples from Northern Italy
  • Discuss the presence of public SARS-CoV-2-specific clonotypes in COVID-19 patient samples and controls
  • Analyze differences in the clonal distribution of SARS-CoV-2-specific T cell clonotypes according to different degrees of disease severity
  • Reveal changes in frequency (expansions vs. contractions) of SARS-CoV-2 clonotypes during evolution of the disease

For Research Use Only. Not for use in Diagnostic Procedures.

Sponsored by

Kaiser Health News reports San Francisco and Alameda counties in California are no longer using Verily Life Sciences' COVID-19 testing program.

The New York Times reports that developers in New York City are increasingly interested in life science spaces.

A UK study has found that antibodies against SARS-CoV-2 may decline over time, Reuters reports.

In PNAS this week: genetic and epigenetic variation in individuals with diabetic kidney disease, spontaneous genetic alterations in Saccharomyces cerevisiae, and more.

Nov
05
Sponsored by
Roche

This webinar will provide an overview of novel proximal and distal sampling methods that have promise to improve patient outcomes from esophageal cancer.

Nov
10
Sponsored by
LGC

The COVID-19 pandemic created a paradigm shift in modern healthcare, where regulations, protocols, and mindsets had to be reworked in just a matter of months to keep up with the pace of the virus.

Nov
17
Sponsored by
ACD

Circular RNAs (circRNAs) have recently gained substantial attention in the cancer research field where most, including the putative oncogene ciRS-7 (CDR1as), have been proposed to function as competitive endogenous RNAs (ceRNAs) by “sponging” specific microRNAs.

Nov
18
Sponsored by
Genomenon

Rapid whole-genome sequencing (rWGS) is an emerging method that can provide molecular diagnosis in time to alter acute medical or surgical management and improve outcomes in acutely ill children.