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August 24, 2020
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High-Definition Spatial Proteomics to Elucidate the Tumor Immune Microenvironment: A Dana-Farber Case Study


This webinar will discuss how high-definition spatial proteomics, enabled by Multiplexed Ion Beam Imaging (MIBI), can be used to explore the immune microenvironment of tumor biopsy samples, illustrated by a case study at Dana-Farber Cancer Institute.

Dana-Farber Cancer Institute is participating in the Human Tumor Atlas Network, a collaborative project funded by the National Cancer Institute that is constructing three-dimensional atlases of the cellular, morphological, molecular features of human cancers over time. 

In this webinar, Scott Rodig of Harvard Medical School will provide an overview of Dana-Farber’s involvement in the Human Tumor Atlas Network and Kyle Wright of Brigham and Women’s Hospital will share a case study, along with validation methods and repeatability metrics. 

The webinar will discuss the role of high-definition spatial proteomics for single-cell phenotype mapping and will review data analysis methods used to generate actionable insights from highly multiplexed, spatial proteomic data. 

Speakers will also share plans for tumor analysis at Dana Farber and the potential future impact of high-definition spatial proteomics for cancer therapeutics.

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AstraZeneca has released its coronavirus vaccine trial protocol, according to the New York Times.

Time magazine looks into how liquid biopsies are changing cancer care.

According to the Guardian, more than 150 countries have signed on to a global SARS-CoV-2 vaccine plan.

In PNAS this week: similar muscle protein patterns across hypertrophic cardiomyopathy phenotypes, analysis of gene expression and brain anatomy in major depression, and more.

Sponsored by
10x Genomics

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease characterized by irreversible scarring of the distal lung, leading to respiratory failure. 

Sponsored by
Akoya Biosciences

Most recent single-cell and spatial biology studies have focused on the network of interactions between different cell types and their spatial context.