April 18, 2017
Sponsored by
Twist BioScience

CRISPR/CAS9 Screening in Human Pluripotent Stem Cells for Target Discovery

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This webinar covers methodologies for genome-wide screening with CRISPR/Cas9 in human pluripotent stem cells (hPSCs) and their neuronal progeny.

CRISPR/Cas9 has revolutionized the ability to precisely modify genomes and to conduct genome-wide screens in human cells. While some cell types are easily modified, hPSCs poorly tolerate Cas9 editing and are difficult to engineer.

Our speaker, Robert Ihry of the Novartis Institutes for Biomedical Research, discusses a method he has developed for efficiently engineering and screening in hPSCs using a drug-inducible Cas9.

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