Biomarker Strategies for Advanced Immune Based Therapies

February 10, 2020

Biomarker Strategies for Advanced Immune Based Therapies

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Due to low response rates, researchers and drug developers continue to seek ways to indicate response or non-response as early as possible. Naval Daver of MD Anderson Cancer Center discusses advanced immune-based approaches in acute myeloid leukemia that combine chemotherapy with checkpoint therapy, along with the relevant biomarker strategies associated with each.

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Nature Papers Present Way to Analyze Cancer Mutational Signatures, Explore Treatment Resistance in Lung Cancer, More

In Nature this week: framework for analyzing cancer mutational signatures, treatment resistance in small cell lung cancer followed by increased intratumoral heterogeneity, and more.

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CAS-CLOVER The clean alternative to CRISPR/Cas9 for gene editing in the drug discovery and development industry

A Machine-Learning Framework for Accurate Classification and Quantification of Oncogenic Variants Using the QuantideX NGS DNA Hotspot 21 Kit

BCR-ABL1 Minor Breakpoint (e1a2) Monitoring Using an Analytically Validated Multiplex Assay

Modifications to RNA Isolation Protocols Meet Requirements for Modern CML Monitoring of BCR-ABL1 Transcript Levels

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Long-Read Sequencing of Human Transcription Provides Insights into Metastatic Cancer

This webinar will discuss a study that used long-read transcriptome sequencing to explore the distribution of isoforms in colon cancer samples and their metastasis counterparts.

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Transformation of the Lab to Fight Genetic Illnesses in the Amish and Mennonite Populations

This webinar will explain how the Clinic for Special Children in Strasburg, Pennsylvania, has transformed its DNA workflows to improve the diagnosis and treatment of genetic illnesses that are prevalent in the pediatric population of its community.

Feb

27

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Digital PCR Method Development for Accurate Quantification of Copy Number Variations

Since the publication of the “The Digital MIQE Guidelines: Minimum Information for Publication of Quantitative Digital PCR Experiments” (dMIQE) in 2013, there has been a large expansion of the applications of dPCR such as single nucleotide variations (SNVs) and copy number variations (CNVs) measurements associated with disease diagnostics.

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The Role of Single-Cell Functional Biomarkers in Next-Generation Cancer Therapies

This webinar will discuss the application of single-cell proteomics and immune-imaging in adoptive cell therapy (ACT) for cancer.

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