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April 23, 2021
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Advances in Single-Cell Proteomics: Building a Complete Picture of Cellular Identity


Professor of Biomedical Engineering,
Yale University

Senior Scientist,

Senior Staff Scientist and Team Leader, Integrative Omics group;
Biological Sciences Division, Pacific Northwest National Laboratory

Professor, Department of Pathology,
Stanford University School of Medicine

Director, Single-Cell Proteomics Center & Assistant Professor, Bioengineering;
Northeastern University, College of Engineering

Professor for Quantitative Biomedicine,
University of Zurich

Recent advances in single-cell technologies have provided unprecedented -omic-level insights into cellular heterogeneity and function. Methods for single-cell genomic, transcriptomic, and epigenomic studies are emerging at a rapid pace and contributing to a better understanding of the complexity of biological systems.

Single-cell proteomics promises to build a much more complete picture of cellular identity, because proteins directly carry out cellular function. But the field faces many challenges, largely due to the lack of direct amplification that is possible with nucleic acids. 

This Virtual Roundtable discussion will bring together a panel of experts in the field of single-cell proteomics to discuss the latest advances in the field and obstacles to its progress. They will also discuss the role of single-cell proteomics within the context of emerging integrative disciplines, such as single-cell multiomics studies and spatial biology.

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The FDA and CDC call for a pause in administering Johnson & Johnson's SARS-CoV-2 vaccine while reports of rare blood clots are looked into, reports the Wall Street Journal.

According to the Associated Press, a Swiss program aims to shepherd long-term science projects and diplomacy.

CNN reports that two new studies suggest the B.1.1.7 SARS-CoV-2 variant may be more transmissible, but may not lead to more severe disease.

In PNAS this week: analysis of pathway affecting acute kidney injury, parental-specific allelic expression in horse placenta, and more.

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Recent advances in single-cell technologies have provided unprecedented -omic-level insights into cellular heterogeneity and function. 

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This webinar, the first in our Next-Generation Proteomics for Precision Oncology series, will discuss how proteomics can help overcome the challenges of treating COVID-19 patients with oncologic comorbidities.

Sponsored by
Akoya Biosciences

Single-cell omics assays have become essential tools for identifying and characterizing cell types and states of complex tissues. While each single-modality assay reveals distinctive features about the sequenced cells, true multiomics assays are still in the early stage of development. 

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Join Dr. Heather Fehling, Chief Scientific Officer at Clinical Reference Labs (CRL), as she provides some insights regarding the future applications of PCR testing.