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The emergence of COVID-19 has resulted in the need for NGS strategies for characterizing the SARS-CoV-2 viral genome. Sequencing of the full-length genome is critical for identifying mutational variants and contributing to research in the fields of virology, immunology, epidemiology, and molecular evolution, among others. However, maximizing viral RNA sequencing reads from clinical samples can be challenging, particularly due to the amount of human background that may be present.

In this on-demand webinar, we present a targeted NGS strategy which combines the Swift RNA Library Prep with the Arbor Biosciences myBaits Expert Virus SARS-CoV-2 panel. Combining RNA library prep with hybridization capture results in full-length genome coverage from a limited number of viral genome copies in a mixed sample, maximizing data output and offering an advantageous workflow for virus characterization.

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Partner Webinar

In this webinar, discover how Paragon’s novel CleanPlex® SARS-CoV-2 Research & Surveillance panel uses their multiplex-PCR based targeted sequencing to detect and interrogate the SARS-CoV-2 genome. Turn your lab into a COVID-19 testing powerhouse via sensitive and comprehensive sequencing of the viral genome.

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Partner Webinar

NVIDIA has developed a suite of tools that can greatly decrease the time it takes to analyze sequencing data coming out of short read sequencers. In this talk we will discuss these tools, their features, and how they can apply to workflows in viral pandemics.

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Partner Webinar

A broadcast of a seminar at OHSU, March 2020 featuring Drs Anushka Dikshit and Ciara Martin discussing RNAscope and GeoMx DSP Technologies.

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GenomeWebinar

Professor of Virology, Division of Infection and Immunity, University College London & Great Ormond Street Hospital for Children

 

Target enrichment has been shown to be more sensitive than metagenomic methods and PCR amplicon sequencing for pathogen genomes, and faster than traditional methods for analysis of hard to culture pathogens, for example viruses and some bacteria.

In this webinar, Judith Breuer of University College London & Great Ormond Street Hospital for Children will show how Agilent’s SureSelect targeted enrichment technology:

  • Allows her team to generate high quality consensus sequences and preserves the population structure of minority variant sequences compared to sequencing directly from clinical samples.  
  • Enables them to interrogate clinical samples for better understanding of the evolution of drug resistance and pathogen transmission. 
  • Offers a useful tool study the impact of drugs on pathogens and the recovery of pathogen transcriptomes as part of understanding pathogenesis.

For Research Use Only. Not for use in diagnostic procedures.

Sponsored by
March 31, 2020
Sponsored by
LGC, Biosearch Technologies

Utilizing Targeted SNP-Based Genotyping to Rapidly Introgress Interspecific Germplasm

Partner Webinar

Robert Vaughn at Texas A&M discusses development of KASP assays targeting polymorphisms in the cotton genome. KASP SNP genotyping allows beneficial genes for yield, pest resistance, and drought tolerance to be efficiently bred in to elite commercial cultivars.

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March 31, 2020
Sponsored by
LGC, Biosearch Technologies

Utilization and Implementation of Molecular Markers in a Public Rice Breeding Program

Partner Webinar

Join Adam Famoso, H. Rouse Caffey Endowed Professor of Biological and Agricultural Engineering at LSU, at PAG as he discusses how the LGC Biosearch KASP chemistry and SNPline system is making molecular markers an integral component of the rice development process by lowering the cost per datapoint and increasing throughput.

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March 31, 2020
Sponsored by
LGC, Biosearch Technologies

Rapid Assessment of Novel Alleles and QTL Through Background Genome Selection

Partner Webinar

Join David Francis of Ohio State University at the LGC Biosearch "Accelerating Trait Discovery" workshop at PAG XXV. David discusses how his lab leveraged KASP to develop more than 7,000 SNP assays in tomato, leading his project rapidly from knowledge of sequence variations to functional characterization.

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Partner Webinar

Join Dr. Katherine Steele, Senior Lecturer in Sustainable Crop Production at Bangor University, as she explores how KASP is used to successfully genotype diverse rice varieties, and how KASP technology can be applied in molecular breeding.

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March 27, 2020
Sponsored by
Discovery Life Sciences

Utilization of a Single Strategic Partner for Biospecimens and Genomic Services

Partner Webinar

Presented at ASHG, October 29, 2019
by Dr. Shawn Levy, Chief Scientific Officer, Genomics

Including Significantly Improved Methods for FFPE RNA Extraction and Whole Exome Sequencing with Deep Coverage of Solid Tumor Variants.

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Partner Webinar

As next-generation DNA sequencing technology continues to evolve and become further integrated into routine clinical testing, the need for efficient and accurate clinical interpretation of oncology diagnostic tests becomes even more pressing. Standard sequencing panels are growing, drugs are covering more targets and pathways, and the expansion of the scientific and clinical literature has become exponential, presenting a significant challenge to laboratory directors and clinicians who need to understand the implications of the test results. QIAGEN provides flexible clinical interpretation solutions, presenting up-to-date drug approvals, treatment guidelines, and biological and clinical evidence


In this webinar, we will focus on how clinical diagnostic labs can accelerate test turnaround times and improve reporting capabilities for somatic sequencing tests in oncology with QCI Precision Insights. A professional clinical interpretation service powered by a world-class team of molecular biologists and oncologists, QCI Precision Insights translates molecular data specific to each patient into state-of-the-art clinical insights and country-specific therapeutic options within minutes. QCI Precision Insights has expanded its service to molecular pathology labs in Europe.

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Partner Webinar

In this on-demand webinar, ACD demonstrates the utility of the RNAscope technology in elucidating direct effects of inflammatory cues on intestinal stem cells (ISCs), and their niche, during pathogenesis of intestinal bowel disease (IBD) and other inflammatory diseases.

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Partner Webinar

Watch scientists describe the power of in situ transcriptomics and discuss the application of this technology to large-scale tissue mapping in the mouse brain. They explain how RNAscope Multiplex Fluorescence assays complement single-cell RNA sequencing. 

Science Webinar Series: Harnessing in situ transcriptomics to reveal complex tissue architecture at single-cell resolution.
Presenter: Omer Bayraktar, Ph.D., Wellcome Sanger Institute, Hinxton, UK

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Partner Webinar

In this on-demand webinar, David Saul and Jo Stanton highlight the quality of DNA extracted using the rapid PDQeX protocol compared to competing methodologies. The speakers also discuss the particular advantages of using this enzyme-driven chemistry for sequencing projects and share insights on the compatibility of the PDQeX system with emerging sequencing technologies.

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February 24, 2020
Sponsored by
Thermo Fisher Scientific

NGS Masters: Whole-Genome Sequencing of cfDNA and ctDNA

Partner Webinar

Whole-genome sequencing is suitable for the study of disease-specific genomic abnormalities from cfDNA. The Invitrogen Collibri PS DNA Library Prep Kit for Illumina Systems enables consistent and reproducible cfDNA library preparation from human plasma samples. 

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Pages

New analyses indicate female researchers are publishing less during the coronavirus pandemic than male researchers, according to Nature News.

A study suggests people with the ApoE e4 genotype may be more likely to have severe COVID-19 than those with other genotypes, the Guardian says.

Direct-to-consumer genetic testing companies are searching for a genetic reason for why some people, but not others, become gravely ill with COVID-19, the Detroit Free Press reports.

In PNAS this week: forward genetics-base analysis of retinal development, interactions of T cell receptors with neoantigens in colorectal cancer, and more.

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