The emergence of COVID-19 has resulted in the need for NGS strategies for characterizing the SARS-CoV-2 viral genome. Sequencing of the full-length genome is critical for identifying mutational variants and contributing to research in the fields of virology, immunology, epidemiology, and molecular evolution, among others. However, maximizing viral RNA sequencing reads from clinical samples can be challenging, particularly due to the amount of human background that may be present.
In this on-demand webinar, we present a targeted NGS strategy which combines the Swift RNA Library Prep with the Arbor Biosciences myBaits Expert Virus SARS-CoV-2 panel. Combining RNA library prep with hybridization capture results in full-length genome coverage from a limited number of viral genome copies in a mixed sample, maximizing data output and offering an advantageous workflow for virus characterization.