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The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

Genome-Wide Analysis Sheds Light on Genetics of ADHD

MicroRNA Cotargeting Linked to Lupus

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

Family Genetic Risk Score Linked to Diagnostic Trajectory in Psychiatric Disorders

Study Questions Existence of Fetal Microbiome

Fruit Fly Study Explores Gut Microbiome Effects on Circadian Rhythm

Chronic Kidney Disease Risk Insights Found in Study of Boxer Dog Breed

Allogeneic CAR T-Cell Therapy Assessed in Treatment-Resistant Multiple Myeloma Cases

Study Points to Long-Read Potential in Prenatal Thalassemia Diagnostic Setting

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.