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The Scan

ApoE and COVID-19

A study suggests people with the ApoE e4 genotype may be more likely to have severe COVID-19 than those with other genotypes, the Guardian says.

New analyses indicate female researchers are publishing less during the coronavirus pandemic than male researchers, according to Nature News.

Direct-to-consumer genetic testing companies are searching for a genetic reason for why some people, but not others, become gravely ill with COVID-19, the Detroit Free Press reports.

In PNAS this week: forward genetics-base analysis of retinal development, interactions of T cell receptors with neoantigens in colorectal cancer, and more.

Nobel laureates and scientific societies urge NIH and the Department of Health and Human Services to revisit the recent decision to end funding for a coronavirus grant.

Confidence Boost

A new Pew Research Center poll finds confidence in medical researchers has grown among US adults since the start of the coronavirus pandemic.

Bloomberg reports that BGI's SARS-CoV-2 testing sites in the Middle East have raised concerns among US officials.

In Science this week: machine learning algorithm for faster Mendelian disorder diagnoses, gene linked to safe response to nitrogen-containing bisphosphonates, and more.

According to the Atlantic, the Centers for Disease Control and Prevention and several US states are combining viral and antibody testing data for SARS-CoV-2, making that data hard to parse.

Francis Collins, the director of the US National Institutes of Health, has been awarded the 2020 Templeton Prize.

In Nature this week: method to uncover genetic components of complex traits, novel cytosine base editor, and more.

Flexible Trials

The Los Angeles Times writes that adaptive clinical trials may speed the search for COVID-19 treatments.

Verily is adapting its Project Baseline to study the immune system response to SARS-CoV-2, CNBC reports.

From the US to Israel

Tel Aviv University researchers have traced many coronavirus cases in Israel to a US strain, according to the Jerusalem Post.

In Cell this week: strategy for prophylactic antiviral CRISPR in human cells; influence of obesity, genetics, and hormone signaling on pancreatic ductal adenocarcinoma; and more.

President Donald Trump renews his call in a letter to cease US funding of the World Health Organization if the agency doesn't make changes, USA Today reports.

New UKRI Head Named

ScienceInsider reports the University of Cambridge's Ottoline Leyser is to take over UK Research and Innovation.

From Their Owners

Nature News reports that the two dogs in Hong Kong that tested positive for SARS-CoV-2 likely caught it from their owners.

In PNAS this week: effect of viral infections on transposable elements in fruit flies, gene expression patterns in developing maize cuticles, and more.

The Lancet's Critique

Lancet editorial criticizes the US pandemic response and the minimization of the Centers for Disease Control and Prevention's role in the response.

Moderna says its candidate coronavirus vaccine appears to be able to stimulate an immune response in early testing, according to the New York Times.

Unnecessary Tests?

Reuters reports federal investigators are looking into PerkinElmer's role in an alleged Medicare fraud, though the firm says it is unaware of any investigation.

In PLOS this week: phenome-wide association study of psychiatric disorder polygenic risk scores, CNV patterns in rhesus macaques, and more.

Another Fraud Charge

Prosecutors have added a twelfth fraud charge against former Theranos CEO Elizabeth Holmes, according to the Mercury News.

Catnip Crazed

A comparative genomics study examines how the Nepetoideae lost the ability to produce iridoids and how catnip then regained it, HealthDay reports.

Pages

New analyses indicate female researchers are publishing less during the coronavirus pandemic than male researchers, according to Nature News.

A study suggests people with the ApoE e4 genotype may be more likely to have severe COVID-19 than those with other genotypes, the Guardian says.

Direct-to-consumer genetic testing companies are searching for a genetic reason for why some people, but not others, become gravely ill with COVID-19, the Detroit Free Press reports.

In PNAS this week: forward genetics-base analysis of retinal development, interactions of T cell receptors with neoantigens in colorectal cancer, and more.