A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.
A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.
In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.
Researchers in JAMA Psychiatry find ties between high or low family genetic risk scores and diagnostic stability or change in four major psychiatric disorders over time.
With gut microbiome and gene expression experiments, researchers in PNAS see signs that the microbiome contributes to circadian rhythm synchronicity and stability in fruit flies.
Researchers in PLOS Genetics have tracked down and begun to characterize 21 genetic loci linked to chronic kidney disease in the boxer dog breed.
In an early-stage trial appearing in Nature Medicine, researchers track safety and tolerability of an allogeneic, BCMA-targeting CAR T-cell therapy, while following response rates and duration as secondary endpoints.
Researchers in Clinical Chemistry evaluate a long-read sequencing-based "comprehensive analysis of thalassemia alleles" strategy for finding rare thalassemia variants in amniotic fluid.