The Scan
Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups
Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.
Small Study of Gene Editing to Treat Sickle Cell Disease
In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.
Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds
Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.
Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing
A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.
Melanoma Linked to Altered Gut Microbes in Case-Control Study
A JAMA Dermatology paper points to melanoma-related gut microbial community shifts, along with differences in gut microbiomes of early- or late-stage melanoma cases.
Study Considers Genetic, Social Contributors to Mortality in Black Breast Cancer Survivors
A JAMA Network Open study suggests African ancestry has stronger ties to tumor subtype and aggressiveness than mortality risk, which was influenced by socioeconomic factors.
Alzheimer's Disease Treatment Lecanemab Blocks Plasma Contact System, Study Finds
Researchers elucidate the molecular mechanism through which lecanemab may have a therapeutic benefit in patients with Alzheimer's disease in a study appearing in PNAS.
Female PhD Students Have Fewer Opportunities to Become Inventors Than Male Students
In PNAS, researchers find that male STEM PhD students have a higher chance of filing their first patent during training than female students.
E-Learning Tool Prior to Genetic Counseling Improves Knowledge, Informed Decisions
A study in the Journal of Genetic Counseling finds that participants who watched an educational animated movie before genetic counseling were three times more likely to make an informed choice.
Kākāpō Sequences to Inform Conservation Efforts, Management
Researchers report in Nature Ecology & Evolution that they have sequenced nearly all living kākāpō, a critically endangered parrot from New Zealand.