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Seven Bridges Scientific Advisory Board

Seven Bridges has appointed James Knight, Jan Korbel, Charles Lee, Heng Li, Gholson Lyon, and Gokhan Hotamisligil to its newly formed scientific advisory board. Knight is currently the director of bioinformatics and research scientists at The Knight Lab at Yale University. Korbel is the principal investigator and senior scientists at the European Molecular Biology Laboratory in Heidelberg, Germany. Lee is the scientific director and professor at the Jackson Laboratory for Genomic Medicine. Li is a research scientists at the Broad Institute at MIT and Harvard, working with David Reich and David Altshuler to understand the genetic causes of disease. Lyon is the head of Cold Spring Harbor Laboratory's Lyon Lab and a research scientist at the Utah Foundation for Biomedical Research. Hotamisligil is the James S. Simmons professor of genetics and metabolism and chair of the department of genetics and complex diseases at Harvard University's School of Public Health.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.