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Roger Tsien

Nobel Prize-winning chemist Roger Tsien died on Aug. 24 in Eugene, Oregon. He was professor of pharmacology, chemistry, and biochemistry at the University of California San Diego School of Medicine. His work on illuminating life within living cells through the discovery and development of green fluorescent protein derived from the jellyfish Aequorea victoria led him to co-win the 2008 Nobel in chemistry. That work was done in collaboration with Osamu Shimomura and Martin Chalfie.

The Scan

Team Tracks Down Potential Blood Plasma Markers Linked to Heart Failure in Atrial Fibrillation Patients

Researchers in BMC Genomics found 10 differentially expressed proteins or metabolites that marked atrial fibrillation with heart failure cases.

Study Points to Synonymous Mutation Effects on E. Coli Enzyme Activity

Researchers in Nature Chemistry saw signs of enzyme activity shifts in the presence of synonymous mutations in a multiscale modeling analysis of three Escherichia coli genes.

Team Outlines Paternal Sample-Free Single-Gene Approach for Non-Invasive Prenatal Screening

With data for nearly 9,200 pregnant individuals, researchers in Genetics in Medicine demonstrate the feasibility of their carrier screening and reflex single-gene non-invasive prenatal screening approach.

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.