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Renuka Uppaluri

Alere has appointed Renuka Uppaluri senior vice president of global reasearch and development. In this newly-created role, Uppaluri will be responsible for leading R&D across the firm's Cardiometabolic, Infectious Disease and Toxicology global business units, and she will also lead its enterprise functions of clinical research, discovery and instrumentation. Uppaluri previously led the Respiratory and Monitoring Solutions R&D team at Covidien, and prior to that she was the general manager for GE Healthcare’s Global Diagnostics and X-Ray Imaging Division.

The Scan

Harvard Team Report One-Time Base Editing Treatment for Motor Neuron Disease in Mice

A base-editing approach restored SMN levels and improved motor function in a mouse model of spinal muscular atrophy, a new Science paper reports.

International Team Examines History of North American Horses

Genetic and other analyses presented in Science find that horses spread to the northern Rockies and Great Plains by the first half of the 17th century.

New Study Examines Genetic Dominance Within UK Biobank

Researchers analyze instances of genetic dominance within UK Biobank data, as they report in Science.

Cell Signaling Pathway Identified as Metastasis Suppressor

A new study in Nature homes in on the STING pathway as a suppressor of metastasis in a mouse model of lung cancer.