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Pascale Witz

PerkinElmer has elected Pascale Witz to its board of directors, effective immediately. Witz most recently served as executive vice president of Sanofi's global diabetes and cardiovascular business. Prior to that, she held several leadership positions during 17 years with GE Healthcare, including president and CEO of its medical diagnostics division. Witz also currently serves on the boards of Horizon Pharma, Regulus Therapeutics, Fresenius Medical Care, Savencia, and French-American Foundation-France.

The Scan

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.

Rett Syndrome Mouse Model Study Points to RNA Editing Possibilities

Investigators targeted MECP2 in mutant mouse models of Rett syndrome, showing in PNAS that they could restore its expression and dial down symptoms.

Investigators Find Shared, Distinct Genetic Contributors to Childhood Hodgkin Lymphoma

An association study in JAMA Network Open uncovers risk variants within and beyond the human leukocyte antigen locus.

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.