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M2Gen: Helge Bastian

Health informatics firm M2Gen recently appointed Helge Bastian as president and CEO. Bastian succeeds William Dalton, executive chair of the firm and interim CEO since September 2018. Bastian joins M2Gen from Thermo Fisher Scientific, where he led the sample preparation and synthetic biology businesses as vice president and general manager since 2014. Before that, he held a number of senior leadership positions and served as a member of several executive leadership teams, including managing director and chief commercial officer at Indivumed; vice president of global marketing, business development, and strategy at Sigma-Aldrich (now Merck KGaA); executive vice president of life science services for SGS; and various management positions at Qiagen including vice president of molecular diagnostics, VP of global strategic marketing, and VP of PreAnalytiX, a Qiagen/Becton Dickinson joint venture.

The Scan

Study Finds Sorghum Genetic Loci Influencing Composition, Function of Human Gut Microbes

Focusing on microbes found in the human gut microbiome, researchers in Nature Communications identified 10 sorghum loci that appear to influence the microbial taxa or microbial metabolite features.

Treatment Costs May Not Coincide With R&D Investment, Study Suggests

Researchers in JAMA Network Open did not find an association between ultimate treatment costs and investments in a drug when they analyzed available data on 60 approved drugs.

Sleep-Related Variants Show Low Penetrance in Large Population Analysis

A limited number of variants had documented sleep effects in an investigation in PLOS Genetics of 10 genes with reported sleep ties in nearly 192,000 participants in four population studies.

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.