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Karen Gripp, Peter Krawitz

FDNA has appointed Karen Gripp as CMO and Peter Krawitz as chief data science officer. The maker of the Face2Gene suite of next-generation phenotyping (NGP) applications said in a statement that their combined clinical, research, and development experience "will elevate the use and proven success of NGP technologies that capture, structure, and interpret complex physiological information." Gripp is chief of medical genetics at the AI duPont Hospital for Children and a professor of pediatrics at the Sidney Kimmel Medical College at Thomas Jefferson University. Krawitz is director of the Institute for Genomic Statistics and Bioinformatics at the University of Bonn in Germany and has been working with FDNA on a study called Prioritization of Exome Data By Image Analysis, or PEDIA, to determine the impact of phenotype and facial analysis on molecular interpretation.

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.