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Jaclyn Biegel

Children's Hospital Los Angeles (CHLA) has appointed Jaclyn Biegel as the director of the Center for Personalized Medicine at CHLA. She is a professor of pathology at the Keck School of Medicine at the University of Southern California and also serves as chief of CHLA's new division of genomic medicine in the department of pathology and laboratory medicine. Previously, Biegel has served as director of the Cancer Cytogenetics Laboratory at Children's Hospital of Philadelphia and as a professor of pediatrics in the Perelman School of Medicine at the University of Pennsylvania.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.