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Heidi Rehm

Heidi Rehm last month became chief genomics officer in the Department of Medicine at Massachusetts General Hospital, where she is part of the Center for Genomic Medicine. In her new role, she will focus on the clinical implementation of genomics. Rehm remains medical director of the Broad Institute’s clinical research sequencing platform and an associate professor of pathology at MGH, Brigham and Women’s Hospital, and Harvard Medical School. She is also a leader and principal investigator of ClinGen, and a co-leader of the Broad Center for Mendelian Genomics. Previously, Rehm was the director of the Laboratory for Molecular Medicine at Partners Healthcare Personalized Medicine.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.