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Grannum Sant

Exosome Diagnostics has appointed Grannum Sant as its head of medical affairs. Sant holds an appointment as Professor of Urology at Tufts University, where he has spent more than two decades. He has also served various leadership positions in research and professional societies, including a term as President of the New England Section of the American Urological Association.

Outside of academia, Sant worked as a pharma medical affairs and clinical development executive, serving as a vice president of medical affairs at both Sanofi-Aventis US, and at Genzyme. Most recently he was the medical affairs lead for OPKO Health.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.