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Darrin Crisitello, Nigel Beard, Marcel Roche

Mission Bio has appointed three members to its executive team, including Darrin Crisitello as chief commercial officer, Nigel Beard as senior VP of research and development, and Marcel Roche as senior VP of finance and administration. Prior to Mission Bio, Crisitello led global clinical teams at Color Genomics and Natera. Crisitello has over 19 years of experience in commercial leadership and business development in next-generation sequencing, microfluidics, artificial intelligence, and machine learning, Beard has launched more than 50 products and has been an inventor on more than 40 patents. He has previously worked at firms such as GlaxoSmithKline and Life Technologies, as well as startups like Feetz. Prior to Mission Bio, Roche served as VP of finance at Achaogen and at Guardant Health.

The Scan

Octopus Brain Complexity Linked to MicroRNA Expansions

Investigators saw microRNA gene expansions coinciding with complex brains when they analyzed certain cephalopod transcriptomes, as they report in Science Advances.

Study Tracks Outcomes in Children Born to Zika Virus-Infected Mothers

By following pregnancy outcomes for women with RT-PCR-confirmed Zika virus infections, researchers saw in Lancet Regional Health congenital abnormalities in roughly one-third of live-born children.

Team Presents Benchmark Study of RNA Classification Tools

With more than 135 transcriptomic datasets, researchers tested two dozen coding and non-coding RNA classification tools, establishing a set of potentially misclassified transcripts, as they report in Nucleic Acids Research.

Breast Cancer Risk Related to Pathogenic BRCA1 Mutation May Be Modified by Repeats

Several variable number tandem repeats appear to impact breast cancer risk and age at diagnosis in almost 350 individuals carrying a risky Ashkenazi Jewish BRCA1 founder mutation.