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Cleveland Clinic: Timothy Chan

Timothy Chan has been appointed director of the Center for Immunotherapy and Precision Immuno-oncology at Cleveland Clinic. Chan joins the clinic from Memorial Sloan Kettering Cancer Center and Weill Cornell School of Medicine, where he chaired the immunogenomics and precision oncology platform and was a tenured professor. He also was chair of the translational oncology division. Chan also joins the leadership of the National Center for Regenerative Medicine of Case Western Reserve University; and is on staff at the Genomic Medicine Institute of the Lerner Research Institute and the Department of Radiation Oncology of the Taussig Cancer Institute. He holds an MD and PhD in genetics from Johns Hopkins University, where he also completed a residency in radiation oncology and postdoc in tumor biology.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.