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Charles David Allis, Michael Grunstein

Charles David Allis and Michael Grunstein have been awarded the 2018 Albert Lasker Basic Medical Research award for their discoveries showing how gene expression is influenced by the chemical modification of histones. Allis is the Joy and Jack Fishman Professor at Rockefeller University, where he heads the Laboratory of Chromatin Biology and Epigenetics. Grunstein is professor emeritus in the Department of Biological Chemistry at the David Geffen School of Medicine at the University of California, Los Angeles.

The Scan

Genetic Tests Lead to Potential Prognostic Variants in Dutch Children With Dilated Cardiomyopathy

Researchers in Circulation: Genomic and Precision Medicine found that the presence of pathogenic or likely pathogenic variants was linked to increased risk of death and poorer outcomes in children with pediatric dilated cardiomyopathy.

Fragile X Syndrome Mutations Found With Comprehensive Testing Method

Researchers in Clinical Chemistry found fragile X syndrome expansions and other FMR1 mutations with ties to the intellectual disability condition using a long-range PCR and long-read sequencing approach.

Team Presents Strategy for Speedy Species Detection in Metagenomic Sequence Data

A computational approach presented in PLOS Computational Biology produced fewer false-positive species identifications in simulated and authentic metagenomic sequences.

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.