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All of Us Research Program: Eric Dishman

Eric Dishman, director of the National Institutes of Health's All of Us Research Program, will step down from the role and serve as the program's chief innovation officer. In his new role, Dishman will drive the "strategic and user-centered development of new program features." Dishman, a cancer survivor, said this change would allow him to focus on his long-term health and direct his energies toward patient advocacy activities. The shift in leadership also marks an evolution for the All of Us program "from a startup to a more established organization," he noted. A nationwide search for a new director and CEO of the population health research effort will begin this week. 

The Scan

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.

DNA Storage Method Taps Into Gene Editing Technology

With a dual-plasmid system informed by gene editing, researchers re-wrote DNA sequences in E. coli to store Charles Dickens prose over hundreds of generations, as they recount in Science Advances.

Researchers Model Microbiome Dynamics in Effort to Understand Chronic Human Conditions

Investigators demonstrate in PLOS Computational Biology a computational method for following microbiome dynamics in the absence of longitudinally collected samples.

New Study Highlights Role of Genetics in ADHD

Researchers report in Nature Genetics on differences in genetic architecture between ADHD affecting children versus ADHD that persists into adulthood or is diagnosed in adults.