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Alexander Mackinnon

Alexander “Craig” Mackinnon has become the inaugural director of the Division of Genomics, Diagnostics, and Bioinformatics in the Department of Pathology at the University of Alabama at Birmingham School of Medicine. He will lead ongoing efforts to establish a Precision Diagnostic Laboratory at UAB. 

Mackinnon is a board-certified anatomical and molecular genetic pathologist. Previously, he was associate professor in the Department of Pathology at the Medical College of Wisconsin, where he directed the Clinical and Translational Research Laboratory, which developed multiple sequencing-based panels targeting variants in both DNA and RNA. 

The Scan

Unique Germline Variants Found Among Black Prostate Cancer Patients

Through an exome sequencing study appearing in JCO Precision Oncology, researchers have found unique pathogenic or likely pathogenic variants within a cohort of Black prostate cancer patients.

Analysis of Endogenous Parvoviral Elements Found Within Animal Genomes

Researchers at PLOS Biology have examined the coevolution of endogenous parvoviral elements and animal genomes to gain insight into using the viruses as gene therapy vectors.

Saliva Testing Can Reveal Mosaic CNVs Important in Intellectual Disability

An Australian team has compared the yield of chromosomal microarray testing of both blood and saliva samples for syndromic intellectual disability in the European Journal of Human Genetics.

Octopus Brain Complexity Linked to MicroRNA Expansions

Investigators saw microRNA gene expansions coinciding with complex brains when they analyzed certain cephalopod transcriptomes, as they report in Science Advances.